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Vitamin B Komplex Sanum N

Registration:  No registration in Germany
Administration form:  Ampules
Liquid dilution for injection
Preparation group:  Vitamins
Active ingredient:  Thiamine hydrochloride (vitamin B1), pyridoxine hydrochloride (vitamin B6)
Composition:  1 ampule of 2 ml contains: Medically active substance: 10 mg thiamine hydrochloride (vitamin B1), 5 mg pyridoxine hydrochloride (vitamin B6). Other constituents: benzyl alcohol.
Indication:  Neuritis, neuralgia, trigeminal neuralgia, ischialgia, cervical syndrome, herpes zoster, radiculoneuritis due to degenerative spondylopathy.
Characteristics:  Vitamin B1 (thiamine) in its active form, thiamine pyrophosphate (TPP), plays a crucial role in carbohydrate metabolism. The daily requirement of vitamin B1 depends on the type of nutrition. If mainly carbohydrates are consumed, then the required amount of vitamin B1 increases. A pure vitamin B1 deficiency causes reduced mental and physical power, lack of appetite and muscular atrophy, in particular of the lower extremities. Vitamin B6 (pyridoxine) is found in all living cells, and its effective compound, pyridoxal-5-phosphate, is an indispensable coenzyme in amino acid metabolism. In cases of rich protein nutrition, the vitamin B6 requirement is increased, as well as during pregnancy and in cases of hyperthreodism. Vitamin B6 deficiency can lead to particular forms of anaemia as well as to skin diseases.
Application:  Vitamin B Komplex Sanum N has to be injected slowly intravenously or intramuscularly. Unless otherwise prescribed: For initial treatment during the first days of therapy intramuscular injection daily with 1 ampule of 2 ml; after beginning recovery, 1 ampule of 2 ml 2-3 x weekly.
Side effects:  In individual cases, hypersensitivity reactions with urticaria and states of shock, particularly in allergy prone patients, may occur. Hypersensitivity caused by benzyl alcohol rarely develops.
Contraindications:  Do not administer in cases of known vitamin B1 hypersensitivity. Vitamin B Komplex Sanum N contains 20 mg benzyl alcohol as preservative; therefore it must not be administered to new-born and undeveloped premature babies.
Adverse reactions:  None known.
Interactions with other remedies:  Vitamin B1 is broken down in infusion solutions containing sulphite. High dosages of vitamin B6 can weaken the effect of L-Dopa. In case of simultaneous use of isoniazid (INH), d-penicillamin and cycloserine, the effect of vitamin B6 can be lowered.
Precautions:  As with all medications and due to the variations of clinical studies, professional medical advice should be sought prior to recommending this product to women during pregnancy or breastfeeding, as well as with children.
Advice:  None.
Duration of treatment:  Dependent on the advice of the physician or health care professional.
How supplied:  The following dosage forms are available: 2 ml ampule 10 and 50.